31.08.2012

Ограничение калорий - работает ли для всех видов?

Много сейчас говорят о таком интересном способе продления жизни как снижение потребляемых калорий. Показано множество успешных результатов на грызунах. Всё очень аргументировано и элегантно. Однако совсем недавно в сети появились сообщения о подобных опытах, проведённых на приматах. И там результаты оказались не столь однозначными. 
Вот одно из таких сообщений:
Calorie Restriction May Make Rats Live Longer, But Doesn’t Work For Primates
Remember those famous studies in worms, mice and rats that indicated that a restricted-calorie diet increased lifespan? Well, the results of a 30-year study in rhesus monkeys has just been reported, and the results make it pretty clear that it doesn’t apply to primates … likely including us.
The molecular pathways and gene circuits that are activated in our bodies as a result of long-term calorie restriction are immensely complicated. Like a tangled ball of yarn complicated. We don’t understand how they work, frankly, and there’s just no magic bullet when it comes to diet and lifespan in creatures like monkeys and humans (I’m looking at you, resveratrol). It’s certainly good for one’s long-term survival not to overeat into Honey-Boo-Boobesity, but what does current science say about calories, long life and naked apes?
Studies of humans who live past 100 point to genetics as more important than restricting calories. Which genes? Time may tell. And none of this has helped us understand how different diet compositions may affect aging.
Read more at Nature News.
Спасибо за наводку jtotheizzoe.

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